Huperzine-A (Huperzia Serrata) Club Moss

Huperzine-A (Huperzia serrata) Chinese Club Moss

Description: 50 mcg, 60 capsules Other Ingredients: Microcrystalline cellulose, hydroxypropyl methylcellulose and maltodextrin. (Vcap). Contains no added starch, salt, wheat, gluten, coloring, or dairy products.

Dosage and Use: One capsule daily, or as recommended by a healthcare practitioner. Do not take more than four doses in any week, and do not use Huperzine A on a chronic basis. Can be taken with or without food.

This standardized extract from the Chinese club moss is an all-natural herbal supplement that benefits healthy levels of acetylcholine. This product is standardized for maximum efficacy.

This extract from Chinese club moss supports memory, focus and concentration. Huperzine stops the enzyme acetylcholinesterase from destroying an important neurotransmitter called acetylcholine. Huperzine also helps protect delicate nerve cells against destruction. Each capsule contains 50 mcg of Huperzine-A.

Huperzine-A Provides Benefits
Huperzine is a unique nutritional supplement that offers hope to those suffering from Alzheimers disease and other age-related mental conditions. Alzheimer's disease is characterized by the destruction of nerve cells in several key areas of the brain devoted to mental functions, including a substantial loss of pre-synaptic cholinergic neurons in brains of patients.

This results in a dramatic decrease in the neurotransmitter acetylcholine, a vital neurotransmitter with a fundamental role in memory and intracellular communication between nerve cells. Research has shown that levels of acetylcholine are deficient in the brains of patients with Alzheimer's disease. What little acetylcholine is still produced in the patients brain is quickly broken down by the brain enzyme, acetylcholinesterase (AChE), leading to a shortage of the neurotransmitter, contributing to the patients loss of memory and other cognitive functions.

Huperzine is derived from the ancient Chinese herb Huperzia serrata, traditionally used for fever, inflammation and irregular menstruation. In the late 1980s, researchers discovered that Huperzine-A, an alkaloid extracted from the raw plant, readily crosses the blood-brain barrier to prevent acetylcholinesterase (AChE) from destroying acetylcholine. Researchers found that Huperzine works in a manner similar to the AChE inhibitors (such as tacrine and donepezil) to impair the ability of AChE to degrade acetylcholine. By inhibiting the actions of AChE and increasing acetylcholine concentrations in the brain, Huperzine-A has been shown to be effective in alleviating some of the symptoms associated with acetylcholine deficiencies.

In one placebo-controlled, double-blinded study, researchers found that 58% of Alzheimers patients experience significant improvement in both cognitive and memory function when given 200 mcg of Huperzine per day. Other significant effects have been noted in patients, both in terms of their life quality and their ability to retrieve past memories. Huperzine's properties suggest that it may be an effective agent for improving memory and learning in healthy humans as well. These findings suggest that Huperzine not only supports the brain from the ill-effects of Alzheimers and senile memory deficits, but also provides a unique and exciting supplement for supporting memory in the healthy aging human as well.

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Warnings and Side Effects:

Keep Huperzine-A (Huperzia serrata) herb/supplements out of reach of children
Do not exceed recommended dose for benefits while avoiding side effects
If you have a bad reaction, discontinue use immediately
When using, please inform your physician.
Since Huperzine A inhibits the enzyme acetylcholinesterase, it should not be used on a chronic basis. The reason for this is that some acetylcholinesterase is needed to suppress excessive amounts of the neurotransmitter acetylcholine from accumulating in the body. While most people over age 30 need more acetylcholine, too much can cause unpleasant side effects. Most healthy people safely boost acetylcholine levels by taking precursors such as choline and phosphatidylcholine along with pantothenic acid. Our Cognitex formula contains these acetylcholine precursor agents.
Do not take Huperzine-A (Huperzia serrata) herb/ supplements if you are taking other acetylcholinesterase inhibitors like Aricept® or Tacrine.

References:
1. JAMA 1994 Apr 6; 271:992-8
2. Nat Struct Biol 1997 Jan;4(1):57-63.) Structure of acetylcholinesterase complexed with huperzine A.
3. Chung Kuo Yao Li, Hsueh Pao16:391-5, 1995.)Efficacy of tablet huperzine-A on memory, cognition, and behavior.
4. Neurosci Lett. 2004 May 6;361(1-3):56-9.
5. Eur J Pharmacol. 2002 Nov 29;455(2-3):101-7.
6. Neuroreport. 1996 Dec 20;8(1):97-101.
7. Pharmacol Biochem Behav. 1995 Jun-Jul;51(2-3):415-9.
8. J Ethnopharmacol. 1994 Dec;44(3):147-55.
9. J Neurosci Res. 1989 Oct;24(2):276-85.

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Huperzine-A (Huperzia Serrata) Club Moss - Side Effects/Benefits