Cognitex has been reformulated to
take advantage of new developments and ingredients for cognitive
health. The newest
ingredients in the Cognitex formula are two standardized wild
blueberry extracts that provide the most active constituents
found in this heath-promoting fruit.
Blueberry
anthocyanins are considered nature’s most potent
antioxidants and have demonstrated properties that extend well
beyond suppressing free radicals. Pterostilbene is another
blueberry constituent that helps maintain healthy lipid and
glucose levels in those already within normal range.8
Importantly, through their unique biological effects;
pterostilbene and anthocyanins may help support DNA structure.9
The Life Extension Cognitex
formulas provides blueberry extracts standardized with both
anthocyanins and pterostilbene.
A crucial building block in the
brain is phosphatidylserine (PS). In fact, brain tissues are
especially rich in this brain nutrient, but aging causes a
decline in the PS content of cells throughout the body, which
can lead to cognitive decline.* Phosphatidylserine helps the
brain use its fuel efficiently. By boosting glucose metabolism
and stimulating production of acetylcholine, supplemental
phosphatidylserine has been shown to improve the condition of
patients experiencing age-associated memory impairment or
cognitive decline.10,11
Thus, replacing this brain food is essential.
Life Extension’s new generation
Cognitex formulas now contain a rich PS compound that mimics the
naturally occurring PS in the brain. SharpPS GoldTM fortified
with omega-3 fatty acids, delivers unique brain-health benefits
to help retard the cognitive degeneration so often seen with
advanced age. These unique brain nutrients have been extensively
studied and may be of tremendous benefit for the aging brain.12
More
Protection Against Free Radicals
The brain is a highly active
organ that produces high levels of free radicals from normal
metabolism. These free radicals can bombard the fatty membranes
of neurons and other brain cells causing premature loss of
function. Cognitex contains a number of phytonutrient-based
antioxidants that work best in a lipid (fat) rich environment
like the brain.
While antioxidant nutrients
provide essential free radical protection, many have limited
capacity once they have spared an electron to balance a free
radical. Cognitex now contains a novel rosemary extract that is
rich in carnosic acid, which provides multi-step protection
against free radicals in a process called the carnosic acid
cascade. At each step of free radical interaction a new compound
is formed, which in turn is a powerful antioxidant in itself.
Bioavailable
to the Brain
Nutritional support for the brain
is challenging as a barrier called the blood-brain barrier keeps
out toxins as well as beneficial nutrients and drugs. Cognitex
contains the grape seed extract Leucoselect® Phytosome™.
By
pairing one molecule of proanthocyanidins from grape seed
extract with two molecules of phosphatidylcholine from soy
lecithin in the Phytosome™, the uptake and distribution to
target tissues of the grape seed polyphenols is enhanced.
Once in the brain, the
polyphenols trap dangerous hydroxyl free radicals that turn fat
rancid. These fats make up the outer lipid membrane of trillions
of brain cells. These polyphenols also protect blood circulation
and oxygen flow to the brain by improving the tone and
elasticity of blood vessels.
Molecular
Size Matters
High levels of procyanidins from
grape seed extract does not ensure an extract is going to have a
beneficial effect on the brain. Polyphenols with higher
molecular weight cannot be absorbed. Leucoselect® Phytosome™
contains smaller size molecules for advanced therapeutic
activity as the larger molecules are discarded during the
extraction process.
A
Difference You Can Feel
Taking dietary supplements can
often be an act of faith as we often cannot feel what they are
doing. Cognitex provides the patented, nonstimulant
phytonutrient called Sensoril®. Sensoril® is a proprietary
standardized extract of ashwagandha, also know as “Indian
ginseng,” and used in Ayurvedic traditional medicine for
boosting brain function and alleviating mental fatigue. Advanced
extraction practices now allows for a highly concentrated yet
balanced brain nutrient. The effects can often be felt
immediately with greater alertness and focus but without the
jitteriness of stimulants.
Sensoril® also helps modulate
the stress response resulting in cortisol excretion. Stress can
be very damaging to the brain, especially memory function, and
cortisol stimulates the body to release sugar (glucose) into the
bloodstream. Elevated levels of glucose can accelerate aging and
increase fat storage leading to weight gain, especially in the
abdomen. In addition, the stress-modulating abilities of
Sensoril® can help stress-overeaters especially when it comes
to carbohydrate cravings.
Advanced
Inflammation Protection
Cognitex also contains a
NeuroProtection Complex designed to provide highly concentrated
standardized extracts of hops, ginger and rosemary – known
anti-inflammatory nutrients. Perluxan™ is a phytonutrient
derived from the hops plant that is beginning to be used in
nutritional formulas for chronic inflammatory conditions.
Circulation
is Key to Cognitive Health
Brain cells such as neurons are
fed by blood vessels. Some of these microcapillaries can be so
small that red blood cells carrying oxygen have difficulty
passing through them. Neurons are the key structure for
cognitive functions including memory. Vinpocetine enhances blood
flow by dilating blood vessels and reducing blood viscosity.
Vinpocetine enhances cerebral metabolism by helping to maintain
healthy blood flow and glucose levels in those already within
normal range, which enhances oxygen utilization by neurons.
Additional
Advanced Brain Nutrients
L-alpha glycerylphosphorylcholine
(A-GPC) is naturally present in all the body’s cells. Its
importance to life and safety as a supplement are evidenced by
its substantial presence in human breast milk.13,14
Acetylcholine is an essential neurotransmitter involved in
muscle control, sleep, and cognition. Its decline coincides with
advancing age, and is a hallmark of neurodegenerative decline.
Cognitex provides A-GPC as a crucial building block for the
production of acetylcholine in the brain.15,16
Cognitex is available with
pregnenolone. Concentrations of this critical hormone are much
higher in the brain, and studies show that this hormone has
numerous mental benefits.
All these ingredients work
synergistically to promote optimal cognitex function.
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