Co Q10 Coenzyme, Ubiquinol - Benefits, Supplements, Side Effects

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Co Q10 Supplements Benefits / Side Effects

Life Extension's new Super Ubiquinol is a formulation that significantly increases the amount of CoQ10 absorbed.  Ubiquinol makes CoQ10 more absorbable by the body.  Co-enzyme Q10 is an essential component of the respiratory cycle of the cell that takes place in the mitochondria and generates ATP -- the cells energy currency.

Orally administered CoQ10 goes directly to the mitochondria where it works to regulate the oxidation of fats and sugars into energy ... an important function since the natural production of CoQ10 declines with advancing age.  When the body has an ample amount of side effects free CoQ10, the mitochondria can work most efficiently throughout the entire body, in cells everywhere, including the heart.

When coenzyme Q10 is orally ingested, only a certain percentage is actually absorbed into the bloodstream.  New findings in human subjects indicate that higher doses of coQ10 provide significantly more positive side effects than the doses that supplement users typically take.  Since Japanese pharmaceutical grade CoQ10 is such an expensive nutrient, an alternative to taking higher doses is to increase the amount of CoQ10 that is absorbed.

Life Extension is pleased to announce the availability of a new formulation that significantly increases the amount of CoQ10 absorbed into the bloodstream compared to previous versions.  By delivering so much more CoQ10 into the blood, the new Super Ubiquinol CoQ10 drastically reduces the cost per milligram for consumers.  By taking just one 50 milligram soft gel capsule per day of this new formula, people obtain the benefits of taking higher amounts of regular CoQ10 supplements.


Healthy Mitochondria for Healthy Life

The New Straits Times

03-02-09

The human body is made up of trillions of cells.  How you feel and function depends on how all these cells feel and function.  To stay healthy, each cell must produce its own energy.  Cells cannot borrow energy from each other.

This energy is created by microscopic structures called mitochondria. "Mitochondria are the power plants of our cells," states Simon Melov, director of the genomics core at the Buck Institute for Age Research in Novato, California. "They convert food into energy in the form of Adenosine Triphosphate (ATP), which the body uses to live."

For this to happen, cells require a vitamin - like substance called Coenzyme Q10 (CoQ10).  Most cells contain between 500 and 2,000 mitochondria which account for as much as 60 per cent of the volume of muscle cells and 45 per cent of the volume of heart cells.  Mitochondria are unusual because they have their own genes and their own DNA (all other DNA is found inside the cell's nucleus).  Mitochondrial DNA (mtDNA) is more likely to get damaged in the course of everyday living.  This damage and its side effects have been implicated as a major contributor to the ageing process.  Some researchers believe that damage to the mitochondria may be the ultimate cause of aging.

Mitochondria have been called "the Achilles-heel of the cell in ageing," states lifespan researcher Tory Hagen of the Linus Pauling Institute in Corvallis, Oregon.  Damaged mitochondria can lead to disease.  In fact, more than 200 inherited diseases, including Alzheimer's disease, diabetes, cancer, heart disease and stroke, have been associated with impaired mitochondrial function.

Every time mitochondria make energy, they produce harmful free radicals which, if not neutralised, can cause damage to the mitochondria.  Mitochondria membranes are the key to energy production.  If the membranes are damaged, less energy is produced and toxins and their side effects build up.  To prevent free radical damage, cells recruit a set of antioxidants like a combination of Alpha Lipoic Acid, Acetyl L- Carnitine (ALA) and CoQ10.

"It is possible that weakened mitochondria leave people more susceptible to Parkinson's Disease or accelerates the progression of Alzheimer's," says Mark Mattson, chief of the cellular and molecular neurosciences section of the National Institute on Aging.

1.  CoQ10 is a vital ingredient in energy production.  As we grow older, our body produces less CoQ10 and that's when our energy-producing system starts to slow down.  Our brains are no longer sharp, our hearts do not beat as efficiently, and we tire easily.

Low levels of CoQ10 affect every aspect of life.  It also affects health, which brings on diseases and speed up ageing.  It is not surprising that scientists have regarded the body's energy-producing system as the most basic system.  It is also the master energy system that runs all our body's functions -- circulatory system, immune system, endocrine system and everything else that keeps us alive.  Yet, this most important system has largely been ignored and the result has wrought havoc on the lives of almost everyone older than 30.  In particular, an accelerated drop in CoQ10 is seen in those 40 and older.

What Causes Deficiency?
CoQ10 is produced by the body in a 17 step process that requires at least eight vitamins, trace minerals and the amino acid tyrosine.  A lack of one can hinder the production of CoQ10.  After the age of 20, CoQ10 levels start to decline with the age of 40 being significant.

2. Acetyl-L-Carnitine or ALC is a natural constituent of the inner mitochondrial membrane, especially in heart, brain, and muscle.  Since the levels decline with age, supplementation of ALC is vital as it also helps restore mitochondrial function.

Acetyl-L-Carnitine (ALC) also helps burn fatty acids (fats) for energy and is involved in the transportation of long chain fatty acids into the mitochondria for conversion of energy.  Heart function is affected because the heart becomes starved of its major fuel source, fats.

3. Alpha Lipoic Acid (ALA) is a potent antioxidant.  Studies found that using ALA will dramatically lower oxidative stress, decreasing damage to the mitochondria.

The combination of ALA and ALC may help improve memory and thinking/cognitive performance in older adults.  Again, it involves the mitochondria.  There is evidence that mitochondria in the brain are very important in memory and cognitive functions side effects free.

This article is courtesy of Stay-well to Live-well by Pahang Pharmacy Sdn Bhd.


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Super Ubiquinol Coenzyme Q10 (Co Q10) - Information/Ingredients/Dose | References

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