Chrysin / Piperine Herbal Supplements - Effects / Dose

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Chrysin Herbal Supplements - Side Effects / Dose

Chrysin Herbal Supplements (Flavone X) 5,7-Dihydroxyflavone (does not include piperine - see Super Mira-Forte) A bioflavonoid called chrysin can be extracted from various plants.  Bodybuilders have used it for decades for its positive effects on testosterone.  Because of its poor absorption into the bloodstream, it has not produced the effects users expect.  In a study published in Biochemical Pharmacology (1999, Vol.58), the specific mechanisms of chrysin's absorption impairment were identified, which infers that the addition of a pepper extract (piperine) could significantly enhance the bioavailability of chrysin without side effects.  Pilot studies have found that chrysin is effective when combined with piperine.  The study tested the effects of these natural flavonoids (such as genistein, rutin, tea catechins, etc.) in human fat cell cultures.  Chrysin was the most potent.  The scientists conducting the study concluded by stating that the effects of certain flavonoids may contribute plant-based diets.  Two recent studies have identified specific mechanisms in how chrysin does its job.  These studies demonstrate that chrysin is more potent than other flavonoids (Arch Pharm Res 1999 Jun;22(3):309-12; J Steroid Biochem Mol Biol 1997 Apr;61(3-6):107-15).

The purpose of these studies was to ascertain which fruits and vegetables should be included in the diet of postmenopausal women.   Flavonoids such as chrysin are of considerable interest.  While this effect is most important for women, however, helping aging men has tremendous potential for its natural effects.

Since chrysin is not a patentable drug, don't expect to see a lot of human research documenting its effects.  There is not much economic interest in finding natural solutions.  Aging men are seeking to gain control and often prefer natural sources rather than trying to convince a physician to prescribe a side effect laden drug.

An advantage to using plant extracts in lieu of drugs is that plant extracts typically do not have untoward side effects.  Chrysin, for example, is an antioxidant that possesses vitamin-like effects in the body.  Chrysin is one of many flavonoids being studied as a phyto-extract that may far-reaching health benefits.  This can provide men with a low cost natural supplement that creates significant benefits.

Chrysin has one other property that could add to its potential.  A major cause of dissatisfaction among men is work-related stress and anxiety.  Another problem some men have is "anxiety" that prevents them from being able to perform.  In a study published in Pharmacology Biochemistry and Behavior (1994, Vol 47), mice were injected with a drug, chrysin, or placebo to evaluate the effects these substances had on anxiety and performance levels.  Chrysin was shown to produce effects comparable with drugs, but without sedation and muscle relaxation.  In other words, chrysin produced a relaxing effect in the brain, but with no impairment of motor activity.

In a study published in a 1997 issue of Pharmacology Biochemistry and Behavior (Vol 58, No 4), chrysin displayed potent effects in rats, but did not interfere with cognitive performance.  In this study, chrysin (and other flavonoids) had no ill-effect on training or test session performance.  

Chrysin is being sold to bodybuilders by commercial supplement companies that do not know if their product is favorably modulating testosterone levels in men.  The Life Extension Foundation, on the other hand, has conducted meticulous studies to evaluate the effects of chrysin (combined with piperine [see Super MiraForte] to facilitate absorption) in aging men.  These studies have produced some impressive preliminary data and ongoing research will be reported in the future.

Chrysin Herbal Supplements - (Flavone X) 5,7-Dihydroxyflavone (does not include piperine) -- 30 Capsules / 500 mg each

Ingredients:  Chrysin (5,7-Dihydroxyflavone) is a bioflavonoid found in the plant Passiflora coerula, a member of the passion flower family.  Other ingredients:  Cellulose and magnesium stearate.  Capsule consists of gelatin.

Suggested dietary use:  Take 1 capsule per day with meals, or as directed by your qualified health consultant.

Warnings Information:

• Do not use if taking prescribed medication, are pregnant, lactating, or have prostate or reproductive abnormalities,
• Keep out of reach of children,
• Do not exceed recommended dose,
• If you have a bad reaction or side effects, discontinue use immediately,
• When using Chrysin (w/o piperine) Herbal Supplements (Flavone X) 5,7-Dihydroxyflavone, please inform your physician.

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