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"There have been many proposed reasons for age-related hippocampal decline. This new study suggests that we may now know one of them. Beyond the obvious conclusion that preventing late-life disease would benefit the ageing hippocampus, our findings suggest that maintaining blood sugar levels, even in the absence of diabetes, could help maintain aspects of cognitive health. "More specifically, our findings predict that any intervention that causes a decrease in blood glucose should increase dentate gyrus function and would therefore be cognitively beneficial." The new findings appear in the December issue of the journal Annals Of Neurology. Dr. Marcelle Morrison-Bogorad, director of neuroscience at the US National Institute on Ageing, which co-funded the study, said: "While more research is needed into the complex interaction of late-life disease and how it may affect the hippocampus, this new study is part of an ongoing effort to identify specific areas where interventions might preserve cognitive health." |
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